Lung Adenocarcinoma Panel

Test Information

For Lung Adenocarcinoma, GGC offers amplification and mutation analysis of EGFR exons 18-21, BRAF V600E mutation analysis, PTEN mutation analysis, and a lung adenocarcinoma panel that combines the above analyses into a single test. o Somatic tissue testing: OncoScan assay can identify chromothripsis (genomic instability in the tumor specimens) and copy number gains, losses and LOH along with EGFR, BRAF and PTEN targeted mutation analyses. o Data analysis, interpretation and reporting: Performed adhering to the ACMG clinical laboratory standards for microarray analysis for neoplastic specimens and next-generation sequencing (Genetics in Medicine (2013) 15(9): 733-747).

Turnaround Time

10 days

CPT Code(s)

81406

Cost

$1,000

Clinical Information

Lung cancer is the leading cause of cancer death in the United States with 222,500 new cases (116,990 in men and 105,510 in women) estimated to be diagnosed in 2017 and 155,870 deaths (84,590 men and 71,280 women) per current National Comprehensive Cancer Network (NCCN) Guidelines (version 5.2017) for non-small cell lung cancer (NSCLC). Lung Adenocarcinoma (LA) is the most common form of lung cancer reported in the U.S. and is the most common type seen in non-smokers. Despite a 5-year relative survival rate of only 17.7% from 2006-2012, recent research has identified several biomarkers in lung adenocarcinoma with predictive and prognostic significance.

Indications

Gene sequencing and targeted mutation testing and copy number analysis can serve as a useful diagnostic and potentially prognostic tool for the analysis of affected tissues or tumors. The detection of copy number variants or specific gene mutations may enhance treatment decisions.

Specimen Requirements

Analysis can be performed on fresh or frozen tissue samples as well as formalin-fixed, paraffin-embedded tissue samples.

Transport Instructions

The specimen should be kept at the appropriate temperature and delivered via overnight shipping.

Have Questions Need Support?

Call our laboratory at 1-800-473-9411 or contact one of our Laboratory Genetic Counselors for assistance.
Robin Fletcher, MS, CGC
Kellie Walden, MS, CGC

Oncology Testing, Panel
Meet The Jones Family

Meet The Jones Family

The journey to becoming parents did not start as an easy one for my husband and I. We suffered the heartache of miscarriage and the unimaginable pain of burying our first born child. Our son, sweet 1 lb 1.4 ounce, 12 inches long, teeny, tiny little Joseph “Hamilton” Jones was born with spina bifida, hydrocephalus, and a heart defect. It tore our hearts out leaving the hospital without him, knowing our dreams and hope for the future were shattered. ...

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