Carnitine Analysis, Total and Free (Plasma, Urine)

Test Information

Carnitine plays an important role in the transport of long chain fatty acids into the mitochondria as well as the formation of acylcarnitines.

Turnaround Time

10 days

CPT Code(s)

82379

Cost

$120

Indications

Measurement of free and total carnitine levels are important for determining the validity of acylcarnitine profiles as well as following patients under carnitine supplementation.

For patients with low plasma carnitine and a suspected carnitine uptake disorder, urine carnitine (total and free) is available as further testing.

Methodology

tandem mass spectrometry (MS-MS)

Specimen Requirements

Plasma Carnitine: 5-7 mL of peripheral blood should be collected in a sodium heparin blood tube. Sample should be spun down; remove plasma and freeze prior to shipment. Approximately 1 mL of plasma is needed for analysis. Blood spots are not acceptable.

Urine Carnitine: 5 mL of random catch urine is requested. The minimum volume required is 1 mL. Samples must be frozen prior to shipping . Samples should be sent frozen by overnight delivery services or courier, preferably on dry ice. If the sample can be delivered the same day, it may be sent cold or at room temperature.

Transport Instructions

Plasma Carnitine: Frozen plasma samples should be sent via overnight express, preferrably on dry ice.

Urine Carnitine: Samples should be sent frozen by overnight delivery services or courier, preferably on dry ice. If the sample can be delivered the same day, it may be sent cold or at room temperature.

Have Questions Need Support?

Call our laboratory at 1-800-473-9411 or contact one of our Laboratory Genetic Counselors for assistance.
Robin Fletcher, MS, CGC
Kellie Walden, MS, CGC

Analyte Analysis, Analytes and Biomarkers, Biochemical Testing, Newborn Screening Follow-Up
Meet The Jones Family

Meet The Jones Family

The journey to becoming parents did not start as an easy one for my husband and I. We suffered the heartache of miscarriage and the unimaginable pain of burying our first born child. Our son, sweet 1 lb 1.4 ounce, 12 inches long, teeny, tiny little Joseph “Hamilton” Jones was born with spina bifida, hydrocephalus, and a heart defect. It tore our hearts out leaving the hospital without him, knowing our dreams and hope for the future were shattered. ...

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