Hilton, Benjamin

Assistant Director, Cytogenetics Laboratory

Hilton, Benjamin

Dr. Hilton joined the Greenwood Genetic Center as Assistant Director of the Cytogenetics Laboratory in 2019. Before coming to the Greenwood Genetic Center, Dr. Hilton completed his Laboratory Genetics and Genomics fellowship training at the University of Utah, ARUP Laboratories, Salt Lake City, UT. He is a member of the American College of Medical Genetics and Genomics, the American Society of Human Genetics, and the Association for Molecular Pathology.

Contact Information

Office: (864) 388-1068
Fax: (864) 941-8141
bhilton@ggc.org

Education

  • B.S. (Biological Sciences) Clemson University, Clemson, SC, 2008
  • Ph.D. (Biomedical Sciences) East Tennessee State University, Johnson City, TN, 2016
  • Laboratory Genetics and Genomics Fellow – University of Utah, ARUP Laboratories, Salt Lake City, UT, 2016-2019
  • Assistant Director, Cytogenetics Laboratory, Greenwood Genetic Center, 2019 - present

Selected Publications

  • Hilton BA, Liu J, Cartwright BM, Liu Y, Breitman M, Wang Y, Jones R, Tang H, Rusinol A, Musich PR, Zou Y. Progerin sequestration of PCNA promotes replication fork collapse and mislocalization of XPA in laminopathy-related progeroid syndromes. FASEB J. 2017 Sep;31(9):3882-3893.
  • Hilton B, Gopal S, Xu L, Mazumder S, Musich PR, Cho BP, Zou Y. Dissociation Dynamics of XPC-RAD23B from Damaged DNA Is a Determining Factor of NER Efficiency. PLoS One. 2016 Jun 21;11(6):e0157784.
  • Benjamin A. Hilton, Zhengke Li, Phillip R. Musich, Hui Wang, Brian M. Cartwright, Moises Serrano, Xiao Zhen Zhou, Kun Ping Lu, and Yue Zou. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015 Oct 1;60(1):35-46.
  • Hilton, B., Shkriabai, N., Musich, P. R., Kvaratskhelia, M., Shell, S., & Zou, Y. A new structural insight into XPA-DNA interactions. Biosci Rep. 2014 Dec 12;34(6):e00162.
  • Tang, H., Hilton, B., Musich, P.R., Fang, D.Z., and Zou, Y. Replication factor C1, the large subunit of replication factor C, is proteolytically truncated in Hutchinson–Gilford progeria syndrome. Aging Cell. 2012 Apr;11(2):363-5.

 

 

One Mother's Story

One Mother's Story

After a long three-year struggle trying to have children, our son, Charlie, was born on April 18, 2009. He was our miracle...perfect in every way! When Charlie was five days old, our pediatrician called to notify us that one of the numbers from the heel prick test was a bit high. We headed to the hospital that afternoon for more tests. I will never forget the following day. It was cool and crisp - not a cloud in the sky....

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